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SELPHYL® System: Advanced Solution for Preparing Autologous Platelet-Rich Fibrin Matrix (PRFM)

The SELPHYL® System offers a revolutionary approach to preparing Autologous Platelet-Rich Fibrin Matrix (PRFM) for a variety of clinical applications. By harnessing the power of your patient’s own platelets, SELPHYL® ensures the highest quality PRFM with optimal growth factor release, promoting faster healing and enhanced outcomes. With its easy-to-use design and precise preparation, SELPHYL® delivers consistent, reproducible results every time, making it the ideal solution for both practitioners and patients.
The SELPHYL® System sets a new standard in regenerative medicine by providing a next-generation Platelet-Rich Fibrin Matrix (PRFM) that outperforms traditional PRP systems. Unlike conventional PRP, which releases growth factors for only a few hours, SELPHYL® extends growth factor release for up to 7 days, optimizing the healing process and enhancing patient outcomes.With its closed, standardized system, SELPHYL® eliminates variability, ensuring consistent and reproducible results with every use.

The process is simple, efficient, and requires minimal handling, reducing the risk of contamination and user error.

Additionally, SELPHYL® provides full training and ongoing support for your entire staff, empowering your practice with the confidence and expertise to deliver the best possible care.

By choosing SELPHYL®, providers can offer their patients a superior, science-backed solution that maximizes the potential of platelet therapy—setting their practice apart from the competition.

HARNESSING YOUR BODY'S NATURAL HEALING POWER

System for the Preparation of Autologous
PLATELET-RICH FIBRIN MATRIX (PRFM)

Selphyl   test tube with platelet and fibrin

ABOUT THE SELPHYL® PRFM SYSTEM

 
  • PRFM Scaffold Protects Platelets
  • Platelets Release Growth Factors Up to 7 Days
  • Easy to Use and Reproducible
  • Full Training and Continued Support for Staff
 

SELPHYL  PRP (LP-PRP)​

  • SELPHYL  PRP tube technology was the most consistent and reproducible system tested in an independent study from Stanford (Dragoo et al.)
  • Leukocyte poor and red blood cell free (Dragoo et al.)
  • ​Low blood draw (9-18ccs) & short spin time (6 min)
  • ​Closed system, preloaded with sodium citrate anticoagulant; no buffering required when using sodium citrate vs. ACD-A (Mishra et al.)
  • ​Long history of safety and efficacy​
  • ​4cc & 8cc PRP volumes
  • ​Up to 2-year shelf-life
 

The Next Generation PRP

  • 9cc Blood Draw

  • 6 Minute Spin

  • Preloaded With Anticoagulant

  • Proprietary Separator Gel

  • Leukocyte Poor

  • Peer-reviewed published support

  • Easy Preparation

  • Consistent and Reproducible Results

  • Closed Transfer System

  • Reasonable Centrifuge program

Selphyl Procedure Video on Vimeo

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PLATELETS RELEASE GROWTH FACTORS

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SELPHYL® PRFM SYSTEM

WHERE IS PRP BEING EVALUATED?
Many active patients are familiar with repetitive or overuse injuries that can cause micro tears of the muscle and/or tendon fibers, resulting in weakness and pain at the injury site.

This can be an acute or chronic condition that can affect the normal healing process of the damaged tissue. Recent studies have evaluated the use of Platelet-Rich Plasma (PRP) to treat these conditions.

It's important to speak with your treating physician to learn more about the studies that have been published evaluating the use of PRP.


NON-SURGICAL TREATMENT APPROACHES TO UNRESPONSIVE INJURIES
Patients who are interested in exploring non-surgical treatment options before resorting to surgery may want to consider Platelet-Rich Plasma (PRP).

Traditional non-surgical interventions include: Corticosteroid ("cortisone") injections, oral anti-inflammatory medications, exercise and bracing. In many cases these modalities may not cure the condition, whereupon PRP may potentially be of great benefit.


SELPHYL PRP
The SELPHYL  System is designed for the safe and rapid preparation of autologous Platelet Rich Plasma (PRP) from a small sample of blood at the patient point of care. Many PRP systems require operator skill, have varying results and have extensive contamination with red blood cells and white blood cells. SELPHYL  removes virtually all contaminating cells and is not dependent upon operator technique or experience. Think of SELPHYL  as the next generation PRP.
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The Power of Blood

Platelet Release Growth Factors
As part of the body’s capacity to heal itself, platelets and other components in human blood migrate to a site of injury. Platelets are known to release a variety of factors that respond to tissue injury, where they initiate and promote healing. By concentrating platelets at the site of injury, physicians have the potential to enhance the body’s natural capacity for healing

SELPHYL  SCIENCE

 

Screenshot 10 3 2025 191058 www.selphyl.com

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System for the Preparation of Autologous
PLATELET-RICH FIBRIN MATRIX (PRFM)

SELPHYL® PRFM System: The Next Generation of Platelet-Rich Fibrin Matrix

 

SELPHYL® is revolutionizing regenerative medicine with its advanced Platelet-Rich Fibrin Matrix (PRFM) technology. Designed to optimize healing and enhance patient outcomes, SELPHYL® delivers a superior, consistent, and reproducible PRFM formulation that surpasses traditional PRP systems.
 

Why Choose SELPHYL® PRFM?

  • Extended Growth Factor Release – Unlike conventional PRP, which releases growth factors for only a few hours, SELPHYL® extends release up to 7 days, maximizing the regenerative potential.
  • Proven & Standardized Process – SELPHYL® utilizes a closed-system design, eliminating variability and ensuring a pure, leukocyte-poor PRFM with minimal handling.
  • Easy to Use & Reproducible – A straightforward preparation process allows for consistent results every time with minimal training required.
  • Comprehensive Training & Support – We provide full training and continued support to ensure seamless integration into your practice.
 

How Does SELPHYL® Work?

The SELPHYL® system safely and effectively separates platelet-rich plasma (PRP) from the patient’s own blood and converts it into PRFM using a proprietary process. This creates a scaffold that protects and sustains the platelets, allowing for prolonged growth factor release and enhanced healing.

Key Steps: Simple Blood Draw – A small sample is drawn from the patient. Centrifugation – The SELPHYL® system isolates the platelets, removing red and white blood cells. PRFM Formation – The platelets are stabilized in a fibrin matrix, extending the release of regenerative growth factors. Application – The resulting PRFM is applied to the treatment area for enhanced tissue regeneration.

 

Applications Across Specialties

SELPHYL® PRFM is widely used in various medical fields, including:
  • Aesthetic Medicine – Facial rejuvenation, hair restoration, and skin treatments.
  • Orthopedics & Sports Medicine – Accelerating recovery for joint, tendon, and soft tissue injuries.
  • Wound Care – Promoting faster healing of chronic and surgical wounds.
  • Dental & Oral Surgery – Enhancing bone grafting and soft tissue healing.
  • Ophthalmology – Supporting corneal and ocular surface regeneration.
 

The SELPHYL® Advantage

With SELPHYL®, you are investing in a scientifically backed, cutting-edge PRFM system that enhances patient care and delivers measurable results. Whether you are looking to improve healing, reduce recovery time, or offer an advanced regenerative solution, SELPHYL® is the gold standard in PRFM technology.

Ready to Elevate Your Practice?
Join the growing number of physicians using SELPHYL® to transform patient outcomes. Contact us today to learn more or schedule a demonstration.
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THE SELPHYL® System
WHAT ITEMS ARE INCLUDED IN YOUR PRFM KIT?

The SELPHYL® System quickly and safely prepares Platelet-rich Fibrin Matrix (PRFM) from a small blood sample, eliminating contamination and operator variability. It converts PRP into PRFM, creating a protective scaffold for platelets.

SELPHYL® PRFM is the next generation of PRP.

Contact Us Today For A Quote
The SELPHYL® System sets a new standard in regenerative medicine by providing a next-generation Platelet-Rich Fibrin Matrix (PRFM) that outperforms traditional PRP systems. Unlike conventional PRP, which releases growth factors for only a few hours,

SELPHYL® extends growth factor release for up to 7 days, optimizing the healing process and enhancing patient outcomes.With its closed, standardized system, SELPHYL® eliminates variability, ensuring consistent and reproducible results with every use.

The process is simple, efficient, and requires minimal handling, reducing the risk of contamination and user error.

Additionally, SELPHYL® provides full training and ongoing support for your entire staff, empowering your practice with the confidence and expertise to deliver the best possible care.

By choosing SELPHYL®, providers can offer their patients a superior, science-backed solution that maximizes the potential of platelet therapy—setting their practice apart from the competition.

 
Learn More

*Purchase 12 Selphyl PRP kits at regular price and receive a FREE CENTRIFUGE

$175 single kit
$300 double kit


* Limit: One free centrifuge per customer
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SELPHYL Testimonial Video

Learn More

Educational Index for Platelet-Rich Plasma/
Platelet-Rich Fibrin Constructs in Orthopaedics.

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